Atractylodis Macrocephalae Extract
Atractylodis Macrocephalae Extract (AME) is a traditional Chinese herbal medicine made from the rhizomes of Atractylodes macrocephala, a perennial plant native to East Asia. It has been used for centuries in Chinese medicine for its various health benefits and is still widely used today.
AME contains various bioactive compounds, including sesquiterpenes, polyacetylenes, flavonoids, and polysaccharides, which contribute to its pharmacological effects. Here are some of the notable pharmacological effects of AME:
1. Anti-inflammatory effects: AME has been shown to exhibit anti-inflammatory effects by reducing the levels of pro-inflammatory cytokines such as interleukin-1β (IL-1β), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6). This effect is attributed to the presence of sesquiterpenes and polyacetylenes in AME.
2. Gastrointestinal effects: AME has been traditionally used to treat gastrointestinal disorders such as diarrhea, nausea, and vomiting. It has been shown to exhibit gastroprotective effects by increasing the production of mucus in the stomach, reducing gastric acid secretion, and protecting the gastric mucosa from damage. This effect is attributed to the presence of polysaccharides in AME.
3. Immunomodulatory effects: AME has been shown to modulate the immune system by increasing the production of immune cells such as T cells and B cells. It has also been shown to enhance the activity of natural killer cells and macrophages, which play a key role in the body's defense against pathogens. This effect is attributed to the presence of polysaccharides and flavonoids in AME.
4. Anti-tumor effects: AME has been shown to exhibit anti-tumor effects by inhibiting the growth and proliferation of cancer cells. It has been shown to induce apoptosis (programmed cell death) in cancer cells, inhibit angiogenesis (the formation of new blood vessels that supply tumors with nutrients), and modulate the expression of genes involved in cell proliferation and survival. This effect is attributed to the presence of sesquiterpenes, polyacetylenes, and flavonoids in AME.
5. Neuroprotective effects: AME has been shown to exhibit neuroprotective effects by reducing oxidative stress, inflammation, and apoptosis in the brain. It has also been shown to enhance cognitive function and memory. This effect is attributed to the presence of polysaccharides and flavonoids in AME.
About us:
Fufeng Sinuote Biotechnology Co., Ltd is situated in Fufeng County, Baoji Province, China within the Jiangba Science and Technology industrial park. Our primary focus is on the research and development, production, and promotion of plant extracts.
Our company possesses various qualifications such as SC, export license, commodity inspection qualification, external inspection report, HACCP, ISO22000, ISO9001, and is also certified as a high-tech enterprise.
We manufacture over 600 types of plant extracts and have our own plant planting base covering an area of more than 1000000 square meters in Gansu & Ningxia Province, China. With over a decade of experience in plant cultivation, we can maintain better control over plant quality, which results in better-quality extract powder.
Our business has been operating in the Plant Extract industry for over ten years, and we have received positive feedback from our numerous clients in many countries.
We also provide the following products: Natural Sweetener Monk Fruit Extract, Natural Vegetable Powder, Paeony Extract, Plant Extract, Platycodon Grandiflorum Root Extract, Polygala Tenuifolia Extract, Polygonatum Sibiricum Extract, Polyphenols Echinacea Purpurea Extract.