Ashwagandha Extract Withanolides

Withanolides are a group of naturally occurring steroid lactones, found in Ashwagandha roots. The standardization of Ashwagandha extract is commonly done by using withanolides as the marker compounds. The minimum recommended percentage of withanolides is 2.5%. Withanolides are responsible for the adaptogenic and anti-inflammatory properties of Ashwagandha.

Ashwagandha Extract Withanolides is a potent Herbal Extract derived from the roots of the Withania somnifera plant, known for its numerous health benefits. Withanolides, the active compounds present in Ashwagandha Extract, contribute to its medicinal properties and therapeutic effects. This extract is often used in combination with other natural ingredients to create various products in the fields of health and wellness.

Amur Corktree Bark Extract and Andrographis Extract are commonly blended with Ashwagandha Extract to enhance its efficacy and broaden its spectrum of benefits. These synergistic combinations create powerful formulations that promote overall well-being and support the body's natural processes.

Furthermore, Ashwagandha Extract Withanolides is utilized in the production of Animal Husbandry Materials, such as feed additives and supplements. Its inclusion in these products aims to improve animal health, enhance immune function, and optimize performance.

In the realm of cosmetics, Ashwagandha Extract Withanolides is utilized as a valuable raw material. When combined with other natural ingredients like Astragalus Extract and Cherry Powder, it contributes to the development of skincare and beauty products. These formulations harness the plant's rejuvenating and antioxidant properties, providing nourishment and protection for the skin.

Ashwagandha Extract Withanolides is also incorporated into various food and beverage applications. Alongside ingredients like Black Walnut Bark Powder, Green Tea Extract, and Fruit Powder, it contributes to the creation of functional foods, dietary supplements, and natural sweeteners. These products cater to different health concerns, such as improving immunity, supporting cardiovascular health, and aiding in weight management.

Other notable applications of Ashwagandha Extract Withanolides include its use in herbal extracts, such as Dong Quai Root Extract, Echinacea Purpurea Extract, and Licorice Root Extract. These combinations serve diverse purposes, ranging from female nourishing products and male sexual enhancement ingredients to help sleeping plant extracts and liver protection fruit powders.

In conclusion, Ashwagandha Extract Withanolides stands as a versatile natural extract, frequently incorporated into various products due to its broad range of health benefits. Its compatibility with numerous ingredients, including those mentioned above, makes it a valuable component in formulations spanning animal husbandry, cosmetics, food, herbal extracts, and more.

Botanical Source: Ashwagandha (Withania somnifera)

Extraction Part: Root

Extraction Method: Ethanol extraction

Extraction Solvent: Ethanol or methanol

Detection Method: HPLC

Odor: Odorless

Color: Light yellow to brownish

Appearance: Powder

CAS Number: 114977-28-5 (withanolide A)

Molecular Formula: C28H38O6

Molecular Weight: 470.60 g/mol

Pharmacological Properties

1. Adaptogenic Properties:

Withanolides have been extensively studied for their adaptogenic properties, which help the body to cope with stress. They work by regulating the levels of cortisol, a hormone released in response to stress. Withanolides help to reduce cortisol levels and thereby reduce the negative effects of stress on the body. This makes Ashwagandha extract a popular herbal supplement for managing stress and anxiety.

2. Anti-Inflammatory Properties:

Withanolides possess potent anti-inflammatory properties that help to reduce inflammation in the body. Studies have shown that withanolides can suppress the activity of pro-inflammatory cytokines, which are responsible for triggering inflammation. This makes Ashwagandha extract an effective natural remedy for reducing joint pain and inflammation.

3. Immunomodulatory Properties:

Withanolides have been found to possess immunomodulatory properties, meaning they can modulate or regulate the immune system. They have been shown to increase the production of white blood cells, which are responsible for fighting infections and diseases. Withanolides also help to regulate the immune response by suppressing the activity of certain immune cells that can cause autoimmune disorders.

4. Antioxidant Properties:

Withanolides are potent antioxidants that help to protect the body from oxidative stress. They work by scavenging free radicals, which are unstable molecules that can damage cells and contribute to the development of various diseases. Withanolides also increase the levels of antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GPx) in the body, which help to protect against oxidative damage.

5. Neuroprotective Properties:

Withanolides have been found to possess neuroprotective properties, meaning they help to protect the brain and nervous system from damage. They have been shown to improve cognitive function, enhance memory and learning, and reduce anxiety and depression. Withanolides also protect against neurodegenerative disorders such as Alzheimer's and Parkinson's disease.

6. Anticancer Properties:

Withanolides have been found to possess anticancer properties, meaning they can inhibit the growth and spread of cancer cells. Studies have shown that withanolides can induce apoptosis (cell death) in cancer cells, inhibit angiogenesis (the formation of new blood vessels), and prevent metastasis (the spread of cancer cells to other parts of the body).